| Sweeten Creek Brewing | 1127 Sweeten Creek Rd | Asheville | North Carolina | 28803-1728 | United States | brewpub | |
| Sycamore Brewing | 2161 Hawkins St Ste A | Charlotte | North Carolina | 28203-5396 | United States | brewpub | |
| Tarboro Brewing Company | 526 N Main St | Tarboro | North Carolina | 27886-4313 | United States | micro | |
| Tek Mountain Brewing | 1844 Sir Tyler Dr | Wilmington | North Carolina | 28405-8305 | United States | micro | |
| The Dreamchaser's Brewery | 115 E North Main St | Waxhaw | North Carolina | 28173-6029 | United States | micro | |
| The Glass Jug | 5410 Nc Highway 55 Ste V | Durham | North Carolina | 27713-7802 | United States | micro | |
| The Laboratory Mill Brewery | 848 Southfork Rd | Lincolnton | North Carolina | 28092 | United States | micro | |
| The Levee Brewing Company, Inc | | Valdese | North Carolina | 28690 | United States | planning | |
| The Olde Mecklenburg Brewery | 4150 Yancey Rd | Charlotte | North Carolina | 28217-1738 | United States | regional | |
| The Other Side of the Moon - Jamestown | 103 W Main St | Jamestown | North Carolina | 27282 | United States | brewpub | |
| The Sycamore Brewing Cannery | 401 W 24th St | Charlotte | North Carolina | 28206-2664 | United States | micro | |
| Thirsty Monk Brewery | 92 Patton Ave | Asheville | North Carolina | 28801-3315 | United States | brewpub | |
| Thirsty Nomad Brewing | 4402 Stuart Andrew Blvd Ste A | Charlotte | North Carolina | 28217-1520 | United States | micro | |
| Thirsty Souls Community Brewing | 238 Market St | Mount Airy | North Carolina | 27030-3514 | United States | micro | |
| Three Spirits Brewery | 5046 Old Pineville Rd Ste 200 | Charlotte | North Carolina | 28217-3033 | United States | micro | |
| Tight Lines Pub | 709 Arendell St | Morehead City | North Carolina | 28557-4214 | United States | brewpub | |
| Tobacco Road Brewery | 505 W Jones St | Raleigh | North Carolina | 27603-1428 | United States | brewpub | |
| Tobacco Wood Brewing Company | | Oxford | North Carolina | 27565 | United States | planning | |
| Top Of The Hill Restaurant and Brewery | 100 E Franklin St Ste F | Chapel Hill | North Carolina | 27514-3629 | United States | brewpub | |
| Traust Brewing Co. | | Charlotte | North Carolina | 28205 | United States | planning | |
| Triple C Brewing | 2900 Griffith St | Charlotte | North Carolina | 28203-5430 | United States | micro | |
| Triskelion Brewing Company | 340 7th Avenue East | Hendersonville | North Carolina | 28792 | United States | micro | |
| Trollingwood Taproom & Brewery | 707 Dickinson Ave | Greenville | North Carolina | 27834-3147 | United States | micro | |
| Trophy Brewing Company | 656 Maywood Ave | Raleigh | North Carolina | 27603-2340 | United States | micro | |
| Turgua Brewing Co | 27 Firefly Hollow Dr | Fairview | North Carolina | 28730-1648 | United States | micro | |
| Twenty-Six Acres Brewing Company | 7285 Westwinds Blvd NW | Concord | North Carolina | 28027-3310 | United States | micro | |
| Twin Leaf Brewery | 144 Coxe Ave | Asheville | North Carolina | 28801-4026 | United States | micro | |
| Unknown Brewing Company | 1327 S Mint St | Charlotte | North Carolina | 28203-4121 | United States | micro | |
| Untapped Territory, LLC | 326 E Main St Ste 1735 | Lincolnton | North Carolina | 28092-3335 | United States | contract | |
| UpCountry Brewing | 1042 Haywood Rd | Asheville | North Carolina | 28806-2639 | United States | brewpub | |
| Uptown Brewing Co | 418 Evans St | Greenville | North Carolina | 27858-1834 | United States | micro | |
| Valley River Brewery & Eatery | 71 Tennessee St | Murphy | North Carolina | 28906-2938 | United States | brewpub | |
| Vecino Brewing | 300 E Main St | Carrboro | North Carolina | 27510-2359 | United States | brewpub | |
| Vicious Fishes Brewery | 219 Fish Dr | Angier | North Carolina | 27501-6077 | United States | micro | |
| Waterline Brewing Co. | 721 Surrey St | Wilmington | North Carolina | 28401-5043 | United States | micro | |
| Waterman's Brewing Co | 1610 Pavillion Pl | Wilmington | North Carolina | 28403-3735 | United States | brewpub | |
| Wedge Brewing Co | 37 Paynes Way Ste 100 | Asheville | North Carolina | 28801-2626 | United States | micro | |
| Weeping Radish Farm Brewery | 6810 Caratoke Hwy | Grandy | North Carolina | 27939-9635 | United States | micro | |
| Westbend Winery and Brewery | 5394 Williams Rd | Lewisville | North Carolina | 27023-8278 | United States | micro | |
| Whistle Hop Brewing Company | 1288 Charlotte Hwy | Fairview | North Carolina | 28730-8797 | United States | micro | |
| White Elephant Beer Company | 225 Market St | Mount Airy | North Carolina | 27030-3513 | United States | micro | |
| White Labs Kitchen and Tap | 172 S Charlotte St | Asheville | North Carolina | 28801 | United States | brewpub | |
| White Street Brewing Company | 218 S White St | Wake Forest | North Carolina | 27587-2742 | United States | micro | |
| White Street Brewing Company - Production Facility | 400 Park Ave | Youngsville | North Carolina | 27596-8688 | United States | micro | |
| Wicked Weed Brewing | 91 Biltmore Ave | Asheville | North Carolina | 28801-3626 | United States | large | |
| Wicked Weed Brewing | 145 Jacob Holme Way | Candler | North Carolina | 28715-0209 | United States | large | |
| Wicked Weed Funk House | 95 Old Shoals Rd | Arden | North Carolina | 28704-9401 | United States | large | |
| Wicked Weed Funkatorium | 95 Old Shoals Rd | Arden | North Carolina | 28704-9401 | United States | large | |
| Wilmington Brewing Company | 824 S Kerr Ave | Wilmington | North Carolina | 28403-8426 | United States | micro | |
| Wise Man Brewing | 826 Angelo Brothers Ave | Winston-Salem | North Carolina | 27101 | United States | micro | |